The quake also jolted the country's capital Islamabad and its sister city Rawalpindi where 17 people were injured and walls of some of the houses of collapsed.
The injured people were shifted to Pakistan Institute of Medical Sciences where a state of emergency has been imposed.
Pervez Khattak, the Chief Minister of the KPK, said that according from reports coming from different parts of the province, the circumstances are appearing to be grim, but the situation with regard to magnitude of the damage done by the quake would become clear till Tuesday.
Xinhua's reporter from Peshawar said that the injured people at the hospitals in Peshawar were brought from the outskirts of the city and most of them got fractures in their limbs.
Xinhua's reporter doing on-the-spot coverage in Peshawar, said that some the inured people narrated to him that they were walking their way home from office when a building collapsed and their bricks hit them.
"I saw the building collapsing, but before I could get away from it the bricks hit me," one of the injured man said.
The media reports said that thousands of houses have been collapsed in KPK, forcing people to stay under open skies where mercury drops down to five in some of the areas on the chilly October nights.
Land sliding was reported in the northern areas of the country and cracks appeared in the glacier in Hunza area.
A glacier also collapsed at the Nanga Purbat, the ninth highest peak of the world located at the north of Pakistan, but no casualty was reported.
Karakoram Highway, the major road in northern areas, was also blocked from five different places due to land sliding, said the ISPR, adding that the Frontier Work Organization is working in the area to clear the roads.
Many tourists including foreigners got stuck in Gilgit-Baltistan and Kashmir areas due to the blockage of the roads by land sliding.
Telecommunication services were suspended in many areas of the country as the strong tremors levelled several mobile towers to ground.
Sports and education activities were halted in many parts of the country following the quake.
Local met office said that the quake hit the country at about 2:09 p.m. (local time) and its epicenter was determined in Mount Hindukush, located along Pakistan-Afghanistan border, with a focal depth of 193 km.
The quake which lasted for about one minute and 10 seconds created panic among the people who rushed out of their houses.
Sohaib, 23, a student from Islamabad told Xinhua that he was attending a class on third floor when the strong tremors were felt and the teachers and all the students rushed their way downstairs which created huge panic.
He said that some of the students also got injured due to the stampede at the stairs of the university.
Talking to media at a hospital in Islamabad, Ali, 18, said that he was sitting on the second floor of the house when he felt the tremors.
"I jumped from the balcony in panic and broke my arm and leg," he said.
About 40 minutes after the quake, a series of aftershocks ranging from 2.5 to 5.3 magnitudes started hitting the country.
The met office said that a total of 14 aftershocks were felt in the same area, adding that more aftershocks of moderate level are feared to hit the country over the next 24 hours.
