The Guangdong zone will deepen economic cooperation between the mainland and neighboring special administrative regions Hong Kong and Macao. It will have three bases in the cities of Guangzhou, Shenzhen and Zhuhai.
The Fujian zone will focus on developing economic cooperation between the mainland and Taiwan. It will cover three areas in Xiamen, Fuzhou and Pingtan, a new industrial park targeting investment from Taiwan.
The Shanghai zone, which has been more than quadrupled in size since it was established, will continue to strive for "the greatest openness" to facilitate investment and trade with currency convertibility and a sound legal environment. It will also further open its service and manufacturing industries.
All zones must adhere to the negative list, which details 122 prohibited or restricted areas for foreign investment, ranging from Internet news services, production of radio and television programs to non-ferrous metal mining. This number has been reduced from 139.
Foreign investors will be subject to the same rules and regulations for new investment as domestic firms.
Experts believe that these fresh zones are strategically important for the "belt and road" initiative, which aims to better connect Asia, Europe and Africa, as a way to boost investment and consumption.
Shao Yu, Shanghai-based chief economist of the Orient Securities Co.,Ltd., said the four FTZs will be crucial "supporting points" for the belt and road initiative.
"More opening-up moves are needed in regions such as southwestern Yunnan and Tibet for the new strategic layout," he said.
Wang Shouwen, assistant minister of commerce, said the new zones will not just copy the Shanghai zone but also break fresh ground in areas such as investment administration, trade regulation and financial systems.
The replication of successful reform measures is a common strategy in the reform and opening-up drive. The Shenzhen Special Economic Zone, founded in 1980, has been rolled out along the entire east coast over the past three decades.
That zone allowed foreign investment to develop the manufacturing industry, a driving force behind the economic boom of previous decades.
FTZ fever has caught the attention of officials across the country, with many pushing for their regions to be included in the next batch of FTZs.
However, observers warn that the central government must ensure that the FTZs are used to pioneer reform measures, and that their policies are correctly implemented.
Foreign business groups have said that the Shanghai zone brought improvements but they expected "more tangible benefits" of financial reforms, such as full convertibility of the yuan.