Technology in question
David Kim, a researcher at South Korea's Sooam Biotech Research Foundation 2006, another co-founder of the Tianjin factory which is set to provide the factory with technological support, told the Global Times they have accumulated the needed technology and experience to produce premium beef breeds through cloning.
But according to the Sooam's website, they mainly clone dogs, including sniffer dogs for South Korean police, Tibetan Mastiffs for Chinese clients and Pugs for the Japanese market.
Kim said Sooam has cloned 753 dogs so far and the average price to clone a pet dog is $100,000. The number of orders is gradually increasing and most of their clients are from the US. He declined to reveal the number of cattle Sooam has cloned.
The factory's planned output of 1 million cattle embryos a year has shocked some experts. In a recent report by Southern Weekly, an unidentified Chinese cloning expert alleged Xu was "talking big," citing the low efficiency of cloning and the difficulty of finding enough surrogate cows to carry hundreds of thousands of embryos.
Irina Polejaeva, associate professor of animal cloning at Utah State University, said based on current technology, 1 million cell-stage embryos can only produce around 15-30 thousand clones due to losses in transfer, pregnancies and births.
Both Xu and Kim acknowledge that the low efficiency of cattle cloning will be a challenge. "It is true that currently cattle cloning efficiency is lower than dog cloning efficiency. However, during the past 10 years, we have been able to increase dog cloning efficiency from less than 1 percent up to more than 30 percent," Kim said.
He claimed that with the joint efforts by Chinese and Korean cloning scientists, the factory will produce increased efficiency.
A scandal involving Sooam's founder and chief scientist Hwang Woo-suk has also raised concerns for the factory's announcement.
According to media reports, Hwang, then a Seoul National University researcher, was dismissed by the university in 2006 and had two papers retracted from the Science journal following accusations that much of his data on somatic cell nuclear transfer was fabricated.
Xu argued that denying all of Hwang's achievements just due to a single scandal is not right. "Sooam's achievements in cloning in recent years are obvious," he noted, saying that Hwang succeeded in cloning eight endangered coyotes in 2011.
Since last summer, Sooam has collaborated with Russia's North Eastern Federal University on cloning the long-extinct mammoth.
Safety worries
The extraordinary claims made by Xu have prompted many Chinese to discuss the safety of cloned beef. On douban.com, a popular online forum, a thread on cloned beef has attracted more than 120 posts, expressing their cautious attitudes.
Despite the high incidence of birth defects and early death among cloned animals, the official risk assessments from several countries including the US and Japan have all shown that food made from clones and their offspring is as safe as that from non-cloned animals.
Still some people reject cloned food. "I will accept cloned food when some others turn out to be healthy after eating it for 30 years," said one netizen.
Governmental attitudes vary globally. Many countries such as the US, Australia and Argentina allow animal cloning.
But the US Food and Drug Administration suggest that "it's important to remember that the primary purpose of clones is for breeding, not eating."
Xu said that's just because the public lacks understanding of cloning. "Many of us are not aware that many plants in the market such as strawberry, tomatoes and bananas, are nurtured through cloning," he said.
There are no cloning-related laws or regulations in China, except ethical conduct guidelines over human embryonic stem research jointly released by the science and health ministries in late 2003, which bans human reproductive cloning but allows stem cell research for therapeutic purposes.
In September last year, the European Parliament voted for a permanent ban on the cloning of all farm animals, imports of cloned livestock and the sale of food from such animals and their offspring.
Flavio Fergnani, Junior Officer of the European Food Safety Authority, told Southern Weekly in a recent report that they made the decision mainly based on the high mortality rate of cloned animals.
Dolly the sheep, the world's first cloned mammal, was euthanized after being diagnosed with a progressive lung disease in 2003 at the age of 6. The Roslin Institute, which cloned the sheep, no longer undertakes research related to cloning of animals.
However, many cloners see the ban as irrational oppression.
Gábor Vajta, Adjunct Professor of Central Queensland University, Australia, and Honorary Professor of Beijing Genomics Institutes, believed it is a "typical example of bad, irrational decisions made by lawyers and politicians," as there's not a single piece of evidence that shows the harmful effect of cloned products.
He hopes the Chinese authorities will support domestic animal cloning and that Chinese cloning enterprises can make breakthroughs.
"A properly designed and well managed venture may prove the value of cloning and help to eliminate the suspicious and negative atmosphere around," he told the Global Times.
Jian Yi, an independent film-maker and cultural activist in China demanded the end of large-scale beef cattle cloning in an article published recently on the theguardian.com, saying that it will bring more pollution, food insecurity and health problems.
Xu is still ambitious. "Given the price of a Wagyu bull ready for slaughter, the value of the factory's annual output will be 12 billion yuan," he claimed.
