Several hundred genes changed in the amount they were being used, including some that are linked to heart disease, cancer, and Type 2 diabetes.
数百种基因的使用状况因为睡眠时长的不同而改变,其中一些基因还与心脏病、癌症以及2型糖尿病有关.
Genes to do with cell repair and replenishment were used much less.
对有关细胞修复与补给的基因的使用大为减少.
Sleep restriction (six and a half to seven hours a night) changed 380 genes.
睡眠的受限（一晚只睡六个半到七个小时）改变了380种基因.
Of these, 220 genes were down regulated by sleep restriction (their power was reduced), while 160 were up regulated (their power was increased).
其中,有220种基因表达下调（他们的活性降低）,另外160种表达上调（他们的活性上升）.
Those affected included body-clock genes which are linked to diabetes.
那些包括控制生物钟在内的基因都受到了影响,而它们又都与糖尿病有关.
One of the most downgraded genes is that which has a role in controlling insulin and is linked to diabetes and insomnia. The most upgraded gene is linked to heart disease.
在表达下调程度最高的基因中,有一种负责控制胰岛素合成的基因与糖尿病和失眠密切相关.而表达上调程度最高的基因则与心脏病有关联.
So changing sleep by tiny amounts can upgrade or downgrade genes that can influence our health and the diseases we become prey to when we sleep too little.
因此,稍微缩短睡眠时长就会改变基因的运作状态,进而影响到我们的身体健康.若是睡得太少,疾病说来就来.
The important message is that getting close to eight hours of sleep a night can make a dramatic difference to our health in just a few days through the way it looks after our genes.
实验所传达的重要信息是,保证每晚近八小时的睡眠是对我们的基因负责；仅仅几天的充足睡眠,我们的健康也会有巨大的改观.
So resist staying up late to listen to another podcast, read one more chapter, have one more drink or do a little bit more work, mistakenly thinking it won't make much difference. It will.
所以说,要是你坚持熬夜再看一个视频,再多读一章小说,再多贪一杯酒或是再多干点儿活,还安慰自己这没什么大不了的话,那你会后悔的.
英文来源：镜报
