冰桶挑战捐款帮助发现致病基因
Ice Bucket Challenge funds gene discovery in ALS (MND) research
The Ice Bucket Challenge that went viral in 2014 has funded an important scientific gene discovery in the progressive neurodegenerative disease ALS, the ALS Association says.
Scientists have identified a new gene contributing to the disease, NEK1.
科学家已经发现了一种导致该病症的新基因NEK1.
The Ice Bucket Challenge has raised $115m from people pouring cold water over themselves and posting the video on social media.
冰桶挑战共募集了1.15亿美元,参与挑战的人们将冰水泼到自己身上,并在社交媒体发布视频.
It was criticised as a stunt, but has funded six research projects.
该活动曾被批为噱头,但所获捐款资助了六个研究项目.
More than 80 researchers in 11 countries searched for ALS risk genes in families affected by the disease.
11个国家的80多位研究员在受病症影响的家族中寻找渐冻症的风险基因.
"The sophisticated gene analysis that led to this finding was only possible because of the large number of ALS samples available," Lucie Bruijn of the ALS Association says.
美国渐冻症协会的科学家露西•布鲁因说："因为有大量可供研究的渐冻症病例,才使复杂的基因分析得以实现,也才有了今天的成果."
The identification of gene NEK1 means scientists can now develop a gene therapy treating it.
NEK1基因的发现意味着科学家们从此可以开发治疗该病症的基因疗法.
Although only 10% of ALS patients have the inherited form, researchers believe that genetics contribute to a much larger percentage of cases.
尽管只有10%的渐冻症患者携带该遗传基因,研究者们认为有更高比例的病例与遗传相关.
Social media was awash with videos of people pouring cold water over their heads to raise money for ALS in the summer of 2014.
