Nanjing Lukou International Airport, in east China's Jiangsu Province, reopened on Thursday morning after a closure of nearly one month.
Flight MU2923 from the airport to the city of Qingdao, Shandong Province, took off at around 10:16 a.m. Thursday, making it the first passenger plane that resumed operation after a COVID-19 resurgence at the airport.
Local authorities have canceled all flights at the airport since the end of July.
A new cluster of infections began to emerge on July 20 when a few cleaners at the Nanjing airport tested positive during routine testing.
Nanjing cleared all medium and high-risk areas for COVID-19 on Aug. 19.