COVID-19 has killed over 100,000 people in the United States since Jan. 1, 2021, according to a tally by Johns Hopkins University on Tuesday evening.
By Wednesday morning, the national death toll from COVID-19 since it first broke out has reached 446,910, with the country's caseload up to 26,436,867.
Over 540 cases of different coronavirus variants have been reported in at least 33 U.S. states as of Tuesday, according to the U.S. Centers for Disease Control and Prevention. Among the cases, a vast majority were caused by the variant B.1.1.7, which was first detected in Britain.