The Cuban government and the EU will sign on Monday a bilateral Political Dialogue and Cooperation Agreement (PDCA), after two decades of frosty ties.
The text should be signed on Monday in Brussels by Cuban Foreign Minister Bruno Rodriguez and the EU's chief diplomat, Federica Mogherini.
Mogherini, who is also the vice-president of the European Commission, was in Havana in March as part of the negotiation process.
"We are at a real turning point in relations between the EU and Cuba. Through this new agreement, the EU shows its willingness to support the process of economic and social modernization in Cuba, and I hope we will continue to advance in our bilateral relations," said Mogherini in a statement this week.
Cuba reacted at the time through Abelardo Moreno, the deputy foreign minister, who led the negotiations with the EU since 2014.
Moreno said that this agreement "will provide for the first time relations between the two parties with a reciprocal, respectful and mutually advantageous contractual framework for the development of political dialogue and cooperation, including the facilitation of trade."
Since 1996, the EU had adopted a Common Position, pushed by Spain, which condition relations with Cuba to the encouragement of democracy and respect for human rights.
This led to a prolonged distance created between Brussels and Havana, with the Cuban government maintaining this was a "selective and discriminatory" policy.
However, after Venezuela, the EU is Cuba's second-largest trading partner, its main foreign investor and the important provider of cooperation funds. The EU has invested heavily in Cuba, especially in the electricity, water, healthcare, food and agriculture sectors.
The agreement signed Monday will remain provisional, until it is ratified by the European Parliament, as well as by each of the member countries. It will engage the EU to relations with Cuba only in areas under Brussels' jurisdiction, such as development and trade.