Resveratrol from red wine, chocolate and grapes was thought to help people keep distance from cancer, and cardiovascular disease.
However, according to a research in Monday's JAMA Internal Medicine, it needs be re-recognized.
The research was conducted on nearly 800 men and women in 65 or older of two villages in the Chianti Region of Italy from 1998 to 2009.
The research leader Dr. Richard Semba said, "When it comes to diet, health and aging, things are not simple and probably do not boil down to one single substance, such as resveratrol".
In order to avoid the pitfalls, these participants had a diet rich in resveratrol to see if resveratrol could lower the risk of those disease and the researchers regularly gathered specimens of subjects' urine and tested them for levels of resveratrol metabolites.
During the follow-up period, the researchers found that over one-third died among those participants, 174 (27.2 percent) developed heart disease and 34 (4.6 percent) developed cancer.
But whether a study participant consumed high levels of resveratrol or none at all, the study revealed no differences in rates of cancer, cardiovascular disease, death or inflammation.
Researcher Rafael deCabo said "There are no data concerning its safety in high doses, or for long-term supplementation in older people, who often...are taking multiple medications".
(Agnencies)
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